Cellular target-engagement reporters advancing discovery,validation and selection in drug development.

KinCon biolabs is a biotech startup based in Innsbruck, Austria. We develop a constantly expanding platform of unique live-cell activity biosensors.

Our Mission

Precision medicine

Reviving enzymes

KinCon biolabs advances the identification of the most efficient, mutation-specific drug candidates to accelerate drug development.

We are setting out to reactivate compartmentalized and mutated enzyme pathways to identify first in class treatments for neurodegenerative disorders.

platform

KinCon biolabs technology platform is geared towards well established as well as hard-to-drug targets.

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Kinases

Nuclear Receptors

p53

E3-Ligases

Conformation reporters for kinases and pseudokinases
Platform established for 100+ kinase variants
Determine drug efficacy and specificity in live-cell assays

First-in-cell readout for nuclear receptor target engagement
Benchmark agonists and antagonists in live-cell assays
Platform coverage for ~25% of all nuclear receptors

Mutation-specific validation of p53 modulators
Profile drug candidates across p53 mutations in live-cell assays
Analyze p53-MDM2 interaction dynamics

Live-cell tracking of E3 ligase conformational dynamics
Analyze targeted protein degradation (TPD) and molecular glue activity
Expandable to emerging and uncharacterized E3 ligases

Technology

The KinCon biosensor platform allows the tracking of drug-induced changes of the protein conformation under physiological relevant conditions.

Protein activity measurements in living cells
Full-length biosensors for the protein of interest are expressed in the target cell-line of choice.
Simple integration of patient mutations for precision medicine
Any mutation of interest can be integrated into the respective biosensor to determine mutation specific drug (candidate) efficacies and specificities.
Systematic analysis
Our technology allows dose- and time-dependent drug profiling in a high content format.

Meet the KinCon biolabs Team

Eduard Stefan

CEO | Co-Founder

Edi is the inventor of the KinCon technology, holds a PhD in genetics and brings more than 15 years of experience in studying the functions of various kinases. He is a group-leader in the institute of molecular biology at the University of Innsbruck.

Philipp Tschaikner

CSO | Co-Founder

Philipp holds a PhD in molecular cell-biology. He is responsible for steering the development of the biosensor platform and implementing our customer-projects.

Andreas Feichtner

Scientist

Andreas, who significantly contributed to the development and application of KinCon technology during his PhD, is now joining KinCon biolabs as a scientist. His expertise and experience will be instrumental in advancing our research and development efforts.

Gabi Reiter

Administration

Gabi plays a vital role at KinCon bio, providing essential administrative support to ensure smooth operations. She brings a high level of organization and dedication to all her tasks, benefiting the entire team.

Alexandra Fritz

Industrial PhD

Alex is a foundational member of KinCon biolabs. She originally joined us as a lab technician, playing a crucial role in developing protocols and processes. Now, she is advancing our R&D efforts as an industrial PhD student, working on her own project.

Ilona Kopp

Technician

Ilona, who joined us in March 2024, is an MD student with a BSc in Molecular Medicine, providing essential support as a lab technician at KinCon biolabs.

Christian Hörtnagl

Technician

Since joining in February 2024, Christian, who holds a BSc in Chemistry, has been instrumental in advancing our lab's research capabilities with his technical proficiency.

Lorenz Klausner

Technician

Lorenz holds a BSc in Chemistry and contributes his expertise to support our innovative research and development projects at KinCon biolabs.

Cellular target-engagement reporters advancing discovery,validation and selection in drug development.

KinCon biolabs is a biotech startup based in Innsbruck, Austria. We develop a constantly expanding platform of unique live-cell activity biosensors.

Our Mission

platform

Technology

Protein activity measurements in living cells

Simple integration of patient mutations for precision medicine

Systematic analysis

Meet the KinCon biolabs Team

Are you interested in our biosensors or just want to connect with us?

Just fill out the form below.

News & Publications

KinCon biolabs Graduates from Creative Destruction Lab (CDL) Program and Joins CDL Supersession in Toronto

KinCon biolabs GmbH Receives Health Hub Tirol Funding

Tracking and blocking interdependencies of cellular BRAF-MEK oncokinase activities

Adress