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October 2022
Resistor: An algorithm for predicting resistance mutations via Pareto optimization over multistate protein design and mutational signatures
April 2021
mTORC2 controls the activity of PKC and Akt by phosphorylating a conserved TOR interaction motif
March 2020
Allosteric Kinase Inhibitors Reshape MEK1 Kinase Activity Conformations in Cells and In Silico
November 2020
Mutation-oriented profiling of autoinhibitory kinase conformations predicts RAF inhibitor efficacies
February 2020
KinCon: Cell‐based recording of full‐length kinase conformations
August 2019
BRAF inhibitors promote intermediate BRAF(V600E) conformations and binary interactions with activated RAS
November 15, 2022
Resistor: An algorithm for predicting resistance mutations via Pareto optimization over multistate protein design and mutational signatures
September 27, 2022
mTORC2 controls the activity of PKC and Akt by phosphorylating a conserved TOR interaction motif
September 27, 2022
Allosteric Kinase Inhibitors Reshape MEK1 Kinase Activity Conformations in Cells and In Silico
September 27, 2022
Mutation-oriented profiling of autoinhibitory kinase conformations predicts RAF inhibitor efficacies
September 27, 2022
KinCon: Cell‐based recording of full‐length kinase conformations
September 27, 2022
BRAF inhibitors promote intermediate BRAF(V600E) conformations and binary interactions with activated RAS